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CATHEPSIN C
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DeCS
Descriptor
English
:
Cathepsin C
Descriptor
Spanish
:
Catepsina C
Descriptor
Portuguese
:
Catepsina C
Synonyms
English
:
Dipeptidyl Peptidase I
Dipeptidyl Aminopeptidase I
Tree Number:
D08.811.277.656.224.130
D08.811.277.656.262.186
D08.811.277.656.350.350.100
Definition
English
:
A papain-like
cysteine
protease that has specificity for amino terminal
dipeptides
. The enzyme plays a
role
in the activation of several pro-inflammatory
serine proteases
by removal of their aminoterminal inhibitory
dipeptides
. Genetic mutations that cause loss of
cathepsin C
activity in
humans
are associated with
PAPILLON-LEFEVRE DISEASE.
History Note
English
:
2010(1981)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
34436
Unique Identifier:
D020789
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS